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Multiple Interactions between Cytoplasmic Domains Regulate Slow Deactivation of Kv11.1 Channels
The intracellular domains of many ion channels are important for fine-tuning their gating kinetics. In Kv11.1 channels, the slow kinetics of channel deactivation, which are critical for their function in the heart, are largely regulated by the N-terminal N-Cap and Per-Arnt-Sim (PAS) domains, as well...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4162183/ https://ncbi.nlm.nih.gov/pubmed/25074935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.558379 |
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