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Druggability assessment of mammalian Per–Arnt–Sim [PAS] domains using computational approaches
Per–Arnt–Sim (PAS) domains are key regions that occur in different regulatory proteins from all kingdoms of life. PAS domains show a remarkably conserved structural scaffold, despite a highly variable primary sequence. In this study we have attempted to address some of the gaps in knowledge regardin...
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| Udgivet i: | Medchemcomm |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Royal Society of Chemistry
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6640724/ https://ncbi.nlm.nih.gov/pubmed/31391885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00148d |
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