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Reaction Mechanism of the Bicopper Enzyme Peptidylglycine α-Hydroxylating Monooxygenase

Peptidylglycine α-hydroxylating monooxygenase is a noninteracting bicopper enzyme that stereospecifically hydroxylates the terminal glycine of small peptides for its later amidation. Neuroendocrine messengers, such as oxytocin, rely on the biological activity of this enzyme. Each catalytic turnover...

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Bibliografiset tiedot
Päätekijät: Abad, Enrique, Rommel, Judith B., Kästner, Johannes
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022847/
https://ncbi.nlm.nih.gov/pubmed/24668808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.558494
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