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Differential Reactivity Between Two Copper Sites in Peptidylglycine α-Hydroxylating Monooxygenase (PHM)
Peptidylglycine α-Hydroxylating Monooxygenase (PHM) catalyzes the stereospecific hydroxylation of the Cα of C-terminal glycine-extended peptides and proteins, the first step in the activation of many peptide hormones, growth factors and neurotransmitters. The crystal structure of the enzyme revealed...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025614/ https://ncbi.nlm.nih.gov/pubmed/20958070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja103117r |
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