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CRISPR-Cas systems for genome editing, regulation and targeting

Targeted genome editing using engineered nucleases has rapidly transformed from a niche technology to a mainstream method used by many biological researchers. This widespread adoption has been largely fueled by the emergence of the clustered regularly interspaced short palindromic repeat (CRISPR) te...

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Detalhes bibliográficos
Main Authors: Sander, Jeffry D., Joung, J. Keith
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022601/
https://ncbi.nlm.nih.gov/pubmed/24584096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2842
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