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TALENs: a widely applicable technology for targeted genome editing
Engineered nucleases enable the targeted alteration of any DNA sequence in a wide range of cell types and organisms. The newly-developed transcription activator-like effector nucleases (TALENs) comprise a non-specific DNA-cleaving nuclease fused to a DNA-binding domain that can be easily engineered...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3547402/ https://ncbi.nlm.nih.gov/pubmed/23169466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3486 |
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