H2rs: Deducing evolutionary and functionally important residue positions by means of an entropy and similarity based analysis of multiple sequence alignments

BACKGROUND: The identification of functionally important residue positions is an important task of computational biology. Methods of correlation analysis allow for the identification of pairs of residue positions, whose occupancy is mutually dependent due to constraints imposed by protein structure...

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Detalhes bibliográficos
Main Authors: Janda, Jan-Oliver, Popal, Ajmal, Bauer, Jochen, Busch, Markus, Klocke, Michael, Spitzer, Wolfgang, Keller, Jörg, Merkl, Rainer
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021312/
https://ncbi.nlm.nih.gov/pubmed/24766829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-118
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