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H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments

BACKGROUND: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to the examination of individual positions, the investigation of co-variation of amino acid frequencies offers insights into...

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Detalhes bibliográficos
Main Authors: Merkl, Rainer, Zwick, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323388/
https://ncbi.nlm.nih.gov/pubmed/18366663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-151
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