Domain within the helicase subunit Mcm4 integrates multiple kinase signals to control DNA replication initiation and fork progression

Eukaryotic DNA synthesis initiates from multiple replication origins and progresses through bidirectional replication forks to ensure efficient duplication of the genome. Temporal control of initiation from origins and regulation of replication fork functions are important aspects for maintaining ge...

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Bibliografiska uppgifter
Huvudupphovsmän: Sheu, Yi-Jun, Kinney, Justin B., Lengronne, Armelle, Pasero, Philippe, Stillman, Bruce
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2014
Ämnen:
PNAS Plus
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020090/
https://ncbi.nlm.nih.gov/pubmed/24740181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1404063111
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