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Mcm10 coordinates the timely assembly and activation of the replication fork helicase

Mcm10 is an essential replication factor that is required for DNA replication in eukaryotes. Two key steps in the initiation of DNA replication are the assembly and activation of Cdc45–Mcm2–7-GINS (CMG) replicative helicase. However, it is not known what coordinates helicase assembly with helicase a...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Perez-Arnaiz, Patricia, Bruck, Irina, Kaplan, Daniel L.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705653/
https://ncbi.nlm.nih.gov/pubmed/26582917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1260
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