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Dpb11 Protein Helps Control Assembly of the Cdc45·Mcm2-7·GINS Replication Fork Helicase

Dpb11 is required for the initiation of DNA replication in budding yeast. Dpb11 binds to S-phase cyclin-dependent kinase-phosphorylated Sld2 and Sld3 to form a ternary complex during S phase. The replication fork helicase in eukaryotes is composed of Cdc45, Mcm2-7, and GINS. We show here, using puri...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Dhingra, Nalini, Bruck, Irina, Smith, Skye, Ning, Boting, Kaplan, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367264/
https://ncbi.nlm.nih.gov/pubmed/25659432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.640383
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