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Concerted activities of Mcm4, Sld3, and Dbf4 in control of origin activation and DNA replication fork progression

Eukaryotic chromosomes initiate DNA synthesis from multiple replication origins in a temporally specific manner during S phase. The replicative helicase Mcm2-7 functions in both initiation and fork progression and thus is an important target of regulation. Mcm4, a helicase subunit, possesses an unst...

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Foilsithe in:Genome Res
Main Authors: Sheu, Yi-Jun, Kinney, Justin B., Stillman, Bruce
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772014/
https://ncbi.nlm.nih.gov/pubmed/26733669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.195248.115
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