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Domain within the helicase subunit Mcm4 integrates multiple kinase signals to control DNA replication initiation and fork progression

Eukaryotic DNA synthesis initiates from multiple replication origins and progresses through bidirectional replication forks to ensure efficient duplication of the genome. Temporal control of initiation from origins and regulation of replication fork functions are important aspects for maintaining ge...

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Detalhes bibliográficos
Main Authors: Sheu, Yi-Jun, Kinney, Justin B., Lengronne, Armelle, Pasero, Philippe, Stillman, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020090/
https://ncbi.nlm.nih.gov/pubmed/24740181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1404063111
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