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The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4

Eukaryotic DNA replication uses kinase regulatory pathways to facilitate coordination with other processes during cell division cycles and response to environmental cues. At least two cell cycle-regulated protein kinase systems, the S phase-specific cyclin-dependent protein kinases (S-CDKs) and the...

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Bibliografiske detaljer
Main Authors: Sheu, Yi-Jun, Stillman, Bruce
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805463/
https://ncbi.nlm.nih.gov/pubmed/20054399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08647
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