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The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4

Eukaryotic DNA replication uses kinase regulatory pathways to facilitate coordination with other processes during cell division cycles and response to environmental cues. At least two cell cycle-regulated protein kinase systems, the S phase-specific cyclin-dependent protein kinases (S-CDKs) and the...

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Библиографические подробности
Главные авторы: Sheu, Yi-Jun, Stillman, Bruce
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805463/
https://ncbi.nlm.nih.gov/pubmed/20054399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08647
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