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Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression
Origins of DNA replication are licensed in G1 by recruiting the mini-chromosome maintenance (MCM) proteins to form a pre-replicative complex. Prior to initiation of DNA synthesis from each origin, a pre-initiation complex (pre-IC) containing Cdc45 and other proteins is formed. We report that Cdc7-Db...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2923825/ https://ncbi.nlm.nih.gov/pubmed/17018296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.07.033 |
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