Fetal programming of adult Leydig cell function by androgenic effects on stem/progenitor cells

Fetal growth plays a role in programming of adult cardiometabolic disorders, which in men, are associated with lowered testosterone levels. Fetal growth and fetal androgen exposure can also predetermine testosterone levels in men, although how is unknown, because the adult Leydig cells (ALCs) that p...

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Bibliographic Details
Main Authors: Kilcoyne, Karen R., Smith, Lee B., Atanassova, Nina, Macpherson, Sheila, McKinnell, Chris, van den Driesche, Sander, Jobling, Matthew S., Chambers, Thomas J. G., De Gendt, Karel, Verhoeven, Guido, O’Hara, Laura, Platts, Sophie, Renato de Franca, Luiz, Lara, Nathália L. M., Anderson, Richard A., Sharpe, Richard M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020050/
https://ncbi.nlm.nih.gov/pubmed/24753613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320735111
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