Fetal programming of adult Leydig cell function by androgenic effects on stem/progenitor cells

Fetal growth plays a role in programming of adult cardiometabolic disorders, which in men, are associated with lowered testosterone levels. Fetal growth and fetal androgen exposure can also predetermine testosterone levels in men, although how is unknown, because the adult Leydig cells (ALCs) that p...

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Autors principals: Kilcoyne, Karen R., Smith, Lee B., Atanassova, Nina, Macpherson, Sheila, McKinnell, Chris, van den Driesche, Sander, Jobling, Matthew S., Chambers, Thomas J. G., De Gendt, Karel, Verhoeven, Guido, O’Hara, Laura, Platts, Sophie, Renato de Franca, Luiz, Lara, Nathália L. M., Anderson, Richard A., Sharpe, Richard M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020050/
https://ncbi.nlm.nih.gov/pubmed/24753613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320735111
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