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Inter-Relationship between Testicular Dysgenesis and Leydig Cell Function in the Masculinization Programming Window in the Rat

The testicular dysgenesis syndrome (TDS) hypothesis proposes that maldevelopment of the testis, irrespective of cause, leads to malfunction of the somatic (Leydig, Sertoli) cells and consequent downstream TDS disorders. Studies in rats exposed in utero to di(n-butyl) phthalate (DBP) have strongly su...

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Detalhes bibliográficos
Main Authors: van den Driesche, Sander, Kolovos, Petros, Platts, Sophie, Drake, Amanda J., Sharpe, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256232/
https://ncbi.nlm.nih.gov/pubmed/22253897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030111
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