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Inter-Relationship between Testicular Dysgenesis and Leydig Cell Function in the Masculinization Programming Window in the Rat

The testicular dysgenesis syndrome (TDS) hypothesis proposes that maldevelopment of the testis, irrespective of cause, leads to malfunction of the somatic (Leydig, Sertoli) cells and consequent downstream TDS disorders. Studies in rats exposed in utero to di(n-butyl) phthalate (DBP) have strongly su...

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Библиографические подробности
Главные авторы: van den Driesche, Sander, Kolovos, Petros, Platts, Sophie, Drake, Amanda J., Sharpe, Richard M.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256232/
https://ncbi.nlm.nih.gov/pubmed/22253897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030111
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