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Dibutyl phthalate induced testicular dysgenesis originates after seminiferous cord formation in rats

Administration of dibutyl phthalate (DBP) to pregnant rats causes reproductive disorders in male offspring, resulting from suppression of intratesticular testosterone, and is used as a model for human testicular dysgenesis syndrome (TDS). DBP exposure in pregnancy induces focal dysgenetic areas in f...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Lara, Nathália L. M., van den Driesche, Sander, Macpherson, Sheila, França, Luiz R., Sharpe, Richard M.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451485/
https://ncbi.nlm.nih.gov/pubmed/28566680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02684-2
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