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Dibutyl phthalate induced testicular dysgenesis originates after seminiferous cord formation in rats

Administration of dibutyl phthalate (DBP) to pregnant rats causes reproductive disorders in male offspring, resulting from suppression of intratesticular testosterone, and is used as a model for human testicular dysgenesis syndrome (TDS). DBP exposure in pregnancy induces focal dysgenetic areas in f...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Lara, Nathália L. M., van den Driesche, Sander, Macpherson, Sheila, França, Luiz R., Sharpe, Richard M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451485/
https://ncbi.nlm.nih.gov/pubmed/28566680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02684-2
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