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Lytic immune synapse function requires filamentous actin deconstruction by Coronin 1A

Lytic immune effector function depends upon directed secretion of cytolytic granules at the immunological synapse (IS) and requires dynamic rearrangement of filamentous (F)-actin. Coronin 1A (Coro1A) is the hematopoietic-specific member of the Coronin family of actin regulators that promote F-actin...

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Detalhes bibliográficos
Main Authors: Mace, Emily M., Orange, Jordan S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020046/
https://ncbi.nlm.nih.gov/pubmed/24760828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314975111
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