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Lytic immune synapse function requires filamentous actin deconstruction by Coronin 1A

Lytic immune effector function depends upon directed secretion of cytolytic granules at the immunological synapse (IS) and requires dynamic rearrangement of filamentous (F)-actin. Coronin 1A (Coro1A) is the hematopoietic-specific member of the Coronin family of actin regulators that promote F-actin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mace, Emily M., Orange, Jordan S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020046/
https://ncbi.nlm.nih.gov/pubmed/24760828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314975111
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