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Lytic immune synapse function requires filamentous actin deconstruction by Coronin 1A

Lytic immune effector function depends upon directed secretion of cytolytic granules at the immunological synapse (IS) and requires dynamic rearrangement of filamentous (F)-actin. Coronin 1A (Coro1A) is the hematopoietic-specific member of the Coronin family of actin regulators that promote F-actin...

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Main Authors: Mace, Emily M., Orange, Jordan S.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020046/
https://ncbi.nlm.nih.gov/pubmed/24760828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314975111
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