Mitochondrial DNA sequence associations with dementia and amyloid-β in elderly African Americans

Mitochondrial dysfunction occurs early in the course of several neurodegenerative diseases, and is potentially related to increased oxidative damage and amyloid-β (Aβ) formation in Alzheimer’s disease. The goals of this study were to assess mtDNA sequence associations with dementia risk, 10-year cog...

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Main Authors: Tranah, Gregory J., Yokoyama, Jennifer S., Katzman, Shana M., Nalls, Michael A., Newman, Anne B., Harris, Tamara B., Cesari, Matteo, Manini, Todd M., Schork, Nicholas J., Cummings, Steven R., Liu, Yongmei, Yaffe, Kristine
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019378/
https://ncbi.nlm.nih.gov/pubmed/24140124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2013.05.023
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