Mitochondrial DNA Heteroplasmy Associations With Neurosensory and Mobility Function in Elderly Adults

BACKGROUND. Mitochondrial DNA (mtDNA) heteroplasmy is a mixture of normal and mutated mtDNA molecules in a cell. High levels of heteroplasmy at specific mtDNA sites lead to inherited mitochondrial diseases with neurological, sensory, and movement impairments. Here we test the hypothesis that heterop...

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Detalles Bibliográficos
Publicado en:J Gerontol A Biol Sci Med Sci
Main Authors: Tranah, Gregory J., Yaffe, Kristine, Katzman, Shana M., Lam, Ernest T., Pawlikowska, Ludmila, Kwok, Pui-Yan, Schork, Nicholas J., Manini, Todd M., Kritchevsky, Stephen, Thomas, Fridtjof, Newman, Anne B., Harris, Tamara B., Coleman, Anne L., Gorin, Michael B., Helzner, Elizabeth P., Rowbotham, Michael C., Browner, Warren S., Cummings, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612388/
https://ncbi.nlm.nih.gov/pubmed/26328603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glv097
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