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Mitochondrial DNA Heteroplasmy Associations With Neurosensory and Mobility Function in Elderly Adults

BACKGROUND. Mitochondrial DNA (mtDNA) heteroplasmy is a mixture of normal and mutated mtDNA molecules in a cell. High levels of heteroplasmy at specific mtDNA sites lead to inherited mitochondrial diseases with neurological, sensory, and movement impairments. Here we test the hypothesis that heterop...

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Bibliografski detalji
Izdano u:J Gerontol A Biol Sci Med Sci
Glavni autori: Tranah, Gregory J., Yaffe, Kristine, Katzman, Shana M., Lam, Ernest T., Pawlikowska, Ludmila, Kwok, Pui-Yan, Schork, Nicholas J., Manini, Todd M., Kritchevsky, Stephen, Thomas, Fridtjof, Newman, Anne B., Harris, Tamara B., Coleman, Anne L., Gorin, Michael B., Helzner, Elizabeth P., Rowbotham, Michael C., Browner, Warren S., Cummings, Steven R.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612388/
https://ncbi.nlm.nih.gov/pubmed/26328603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glv097
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