Mitochondrial DNA sequence associations with dementia and amyloid-β in elderly African Americans

Mitochondrial dysfunction occurs early in the course of several neurodegenerative diseases, and is potentially related to increased oxidative damage and amyloid-β (Aβ) formation in Alzheimer’s disease. The goals of this study were to assess mtDNA sequence associations with dementia risk, 10-year cog...

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Detalhes bibliográficos
Main Authors: Tranah, Gregory J., Yokoyama, Jennifer S., Katzman, Shana M., Nalls, Michael A., Newman, Anne B., Harris, Tamara B., Cesari, Matteo, Manini, Todd M., Schork, Nicholas J., Cummings, Steven R., Liu, Yongmei, Yaffe, Kristine
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019378/
https://ncbi.nlm.nih.gov/pubmed/24140124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2013.05.023
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