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Mitochondrial DNA sequence associations with dementia and amyloid-β in elderly African Americans

Mitochondrial dysfunction occurs early in the course of several neurodegenerative diseases, and is potentially related to increased oxidative damage and amyloid-β (Aβ) formation in Alzheimer’s disease. The goals of this study were to assess mtDNA sequence associations with dementia risk, 10-year cog...

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Détails bibliographiques
Auteurs principaux: Tranah, Gregory J., Yokoyama, Jennifer S., Katzman, Shana M., Nalls, Michael A., Newman, Anne B., Harris, Tamara B., Cesari, Matteo, Manini, Todd M., Schork, Nicholas J., Cummings, Steven R., Liu, Yongmei, Yaffe, Kristine
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019378/
https://ncbi.nlm.nih.gov/pubmed/24140124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2013.05.023
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