Mitochondrial DNA Sequence Variation Associated with Dementia and Cognitive Function in the Elderly

Mitochondrial dysfunction is a prominent hallmark of Alzheimer's disease (AD). Mitochondrial DNA (mtDNA) damage may be a major cause of abnormal reactive oxidative species production in AD or increased neuronal susceptibility to oxidative injury during aging. The purpose of this study was to as...

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Detalhes bibliográficos
Main Authors: Tranah, Gregory J., Nalls, Michael A., Katzman, Shana M., Yokoyama, Jennifer S., Lam, Ernest T., Zhao, Yiqiang, Mooney, Sean, Thomas, Fridtjof, Newman, Anne B., Liu, Yongmei, Cummings, Steven R., Harris, Tamara B., Yaffe, Kristine
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156011/
https://ncbi.nlm.nih.gov/pubmed/22785396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2012-120466
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