Mitochondrial DNA Sequence Variation Associated with Dementia and Cognitive Function in the Elderly

Mitochondrial dysfunction is a prominent hallmark of Alzheimer's disease (AD). Mitochondrial DNA (mtDNA) damage may be a major cause of abnormal reactive oxidative species production in AD or increased neuronal susceptibility to oxidative injury during aging. The purpose of this study was to as...

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Hlavní autoři: Tranah, Gregory J., Nalls, Michael A., Katzman, Shana M., Yokoyama, Jennifer S., Lam, Ernest T., Zhao, Yiqiang, Mooney, Sean, Thomas, Fridtjof, Newman, Anne B., Liu, Yongmei, Cummings, Steven R., Harris, Tamara B., Yaffe, Kristine
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156011/
https://ncbi.nlm.nih.gov/pubmed/22785396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2012-120466
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