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Treatment with the 3-Ketoacyl-CoA Thiolase Inhibitor Trimetazidine Does Not Exacerbate Whole-Body Insulin Resistance in Obese Mice

There is a growing need to understand the underlying mechanisms involved in the progression of cardiovascular disease during obesity and diabetes. Although inhibition of fatty acid oxidation has been proposed as a novel approach to treat ischemic heart disease and heart failure, reduced muscle fatty...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Ussher, John R., Keung, Wendy, Fillmore, Natasha, Koves, Timothy R., Mori, Jun, Zhang, Liyan, Lopaschuk, David G., Ilkayeva, Olga R., Wagg, Cory S., Jaswal, Jagdip S., Muoio, Deborah M., Lopaschuk, Gary D.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The American Society for Pharmacology and Experimental Therapeutics 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019316/
https://ncbi.nlm.nih.gov/pubmed/24700885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.214197
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