Inhibition of Carnitine Palmitoyltransferase-1 Activity Alleviates Insulin Resistance in Diet-Induced Obese Mice

Impaired skeletal muscle fatty acid oxidation has been suggested to contribute to insulin resistance and glucose intolerance. However, increasing muscle fatty acid oxidation may cause a reciprocal decrease in glucose oxidation, which might impair insulin sensitivity and glucose tolerance. We therefo...

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Main Authors: Keung, Wendy, Ussher, John R., Jaswal, Jagdip S., Raubenheimer, Monique, Lam, Victoria H.M., Wagg, Cory S., Lopaschuk, Gary D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Diabetes Association 2013
Ábhair:
Metabolism
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581198/
https://ncbi.nlm.nih.gov/pubmed/23139350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0259
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