Modification of T cell responses by stem cell mobilization requires direct signalling of the T cell by G-CSF and IL-10

The majority of allogeneic stem cell transplants are currently undertaken using G-CSF mobilized peripheral blood stem cells. G-CSF has diverse biological effects on a broad range of cells and IL-10 is a key regulator of many of these effects. Using mixed radiation chimeras in which the haematopoieti...

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Autors principals: MacDonald, Kelli P.A., Le Texier, Laetitia, Zhang, Ping, Morris, Helen, Kuns, Rachel D., Lineburg, Katie E., Leveque, Lucie, Don, Alistair L., Markey, Kate A, Vuckovic, Slavica, Bagger, Frederik Otzen, Boyle, Glen, Blazar, Bruce R, Hill, Geoffrey R.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018243/
https://ncbi.nlm.nih.gov/pubmed/24585878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302315
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