NKT cell–dependent leukemia eradication following stem cell mobilization with potent G-CSF analogs

NKT cells have pivotal roles in immune regulation and tumor immunosurveillance. We report that the G-CSF and FMS-like tyrosine kinase 3 ligand (Flt-3L) chimeric cytokine, progenipoietin-1, markedly expands the splenic and hepatic NKT cell population and enhances functional responses to α-galactosylc...

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Main Authors: Morris, Edward S., MacDonald, Kelli P.A., Rowe, Vanessa, Banovic, Tatjana, Kuns, Rachel D., Don, Alistair L.J., Bofinger, Helen M., Burman, Angela C., Olver, Stuart D., Kienzle, Norbert, Porcelli, Steven A., Pellicci, Daniel G., Godfrey, Dale I., Smyth, Mark J., Hill, Geoffrey R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2005
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1253626/
https://ncbi.nlm.nih.gov/pubmed/16224535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25249
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