NKT cell–dependent leukemia eradication following stem cell mobilization with potent G-CSF analogs

NKT cells have pivotal roles in immune regulation and tumor immunosurveillance. We report that the G-CSF and FMS-like tyrosine kinase 3 ligand (Flt-3L) chimeric cytokine, progenipoietin-1, markedly expands the splenic and hepatic NKT cell population and enhances functional responses to α-galactosylc...

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Autores principales: Morris, Edward S., MacDonald, Kelli P.A., Rowe, Vanessa, Banovic, Tatjana, Kuns, Rachel D., Don, Alistair L.J., Bofinger, Helen M., Burman, Angela C., Olver, Stuart D., Kienzle, Norbert, Porcelli, Steven A., Pellicci, Daniel G., Godfrey, Dale I., Smyth, Mark J., Hill, Geoffrey R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2005
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1253626/
https://ncbi.nlm.nih.gov/pubmed/16224535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25249
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