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A Natural Killer T (NKT) Cell Developmental Pathway Involving a Thymus-dependent NK1.1(−)CD4(+) CD1d-dependent Precursor Stage

The development of CD1d-dependent natural killer T (NKT) cells is poorly understood. We have used both CD1d/α-galactosylceramide (CD1d/αGC) tetramers and anti-NK1.1 to investigate NKT cell development in vitro and in vivo. Confirming the thymus-dependence of these cells, we show that CD1d/αGC tetram...

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Detalhes bibliográficos
Main Authors: Pellicci, Daniel G., Hammond, Kirsten J.L., Uldrich, Adam P., Baxter, Alan G., Smyth, Mark J., Godfrey, Dale I.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193721/
https://ncbi.nlm.nih.gov/pubmed/11927628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20011544
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