The 3-Deoxy Analogue of α-GalCer: Disclosing the Role of the 4-Hydroxyl Group for CD1d-Mediated NKT Cell Activation

[Image: see text] KRN7000, or α-GalCer, is a potent agonist for natural killer T (NKT) cells. The 3-hydroxyl group of its phytosphingosine moiety is important for activating NKT cells, whereas its 4-hydroxyl group is perceived to be less crucial. To experimentally determine the role of the 4-hydroxy...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Baek, Dong Jae, Seo, Jeong-Hwan, Lim, Chaemin, Kim, Jae Hyun, Chung, Doo Hyun, Cho, Won-Jea, Kang, Chang-Yuil, Kim, Sanghee
פורמט: Artigo
שפה:Inglês
יצא לאור: American Chemical Society 2011
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018141/
https://ncbi.nlm.nih.gov/pubmed/24900347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml2000802
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים