The 3-Deoxy Analogue of α-GalCer: Disclosing the Role of the 4-Hydroxyl Group for CD1d-Mediated NKT Cell Activation

[Image: see text] KRN7000, or α-GalCer, is a potent agonist for natural killer T (NKT) cells. The 3-hydroxyl group of its phytosphingosine moiety is important for activating NKT cells, whereas its 4-hydroxyl group is perceived to be less crucial. To experimentally determine the role of the 4-hydroxy...

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Detaylı Bibliyografya
Asıl Yazarlar: Baek, Dong Jae, Seo, Jeong-Hwan, Lim, Chaemin, Kim, Jae Hyun, Chung, Doo Hyun, Cho, Won-Jea, Kang, Chang-Yuil, Kim, Sanghee
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2011
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018141/
https://ncbi.nlm.nih.gov/pubmed/24900347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml2000802
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