Design and Evaluation of ω-Hydroxy Fatty Acids Containing α-GalCer Analogues for CD1d-Mediated NKT Cell Activation

[Image: see text] CD1d molecules recognize glycolipid antigens with straight chain fatty acid moieties. Although most of the residues in the CD1d binding groove are hydrophobic, some of the amino acids can form hydrogen bonds. Consequently, we have designed ω-hydroxy fatty acid-containing glycolipid...

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Main Authors: Lim, Chaemin, Kim, Jae Hyun, Baek, Dong Jae, Lee, Joo-Youn, Cho, Minjae, Lee, Yoon-Sook, Kang, Chang-Yuil, Chung, Doo Hyun, Cho, Won-Jae, Kim, Sanghee
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027640/
https://ncbi.nlm.nih.gov/pubmed/24900836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400517b
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