Preparation, Gram-Negative Antibacterial Activity, and Hydrolytic Stability of Novel Siderophore-Conjugated Monocarbam Diols

[Image: see text] A novel series of monocarbam compounds exhibiting promising antibacterial activity against multidrug resistant Gram-negative microorganisms is reported, along with the synthesis of one such molecule MC-1 (1). Also reported are structure−activity relationships associated with the in...

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Main Authors: Flanagan, Mark E., Brickner, Steven J., Lall, Manjinder, Casavant, Jeffrey, Deschenes, Laura, Finegan, Steven M., George, David M., Granskog, Karl, Hardink, Joel R., Huband, Michael D., Hoang, Thuy, Lamb, Lucinda, Marra, Andrea, Mitton-Fry, Mark, Mueller, John P., Mullins, Lisa M., Noe, Mark C., O'Donnell, John P., Pattavina, David, Penzien, Joseph B., Schuff, Brandon P., Sun, Jianmin, Whipple, David A., Young, Jennifer, Gootz, Thomas D.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Chemical Society 2011
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018130/
https://ncbi.nlm.nih.gov/pubmed/24900319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200012f
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