SAR and Structural Analysis of Siderophore-Conjugated Monocarbam Inhibitors of Pseudomonas aeruginosa PBP3

[Image: see text] A main challenge in the development of new agents for the treatment of Pseudomonas aeruginosa infections is the identification of chemotypes that efficiently penetrate the cell envelope and are not susceptible to established resistance mechanisms. Siderophore-conjugated monocarbams...

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Bibliographic Details
Published in:ACS Med Chem Lett
Main Authors: Murphy-Benenato, Kerry E., Dangel, Brian, Davis, Hajnalka E., Durand-Réville, Thomas F., Ferguson, Andrew D., Gao, Ning, Jahić, Haris, Mueller, John P., Manyak, Erika L., Quiroga, Olga, Rooney, Michael, Sha, Li, Sylvester, Mark, Wu, Frank, Zambrowski, Mark, Zhao, Shannon X.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2015
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434466/
https://ncbi.nlm.nih.gov/pubmed/26005529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00026
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