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Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains of Pseudomonas aeruginosa

Pseudomonas aeruginosa is an opportunistic Gram-negative pathogen that causes nosocomial infections for which there are limited treatment options. Penicillin-binding protein PBP3, a key therapeutic target, is an essential enzyme responsible for the final steps of peptidoglycan synthesis and is coval...

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מידע ביבליוגרפי
Main Authors: Han, Seungil, Zaniewski, Richard P., Marr, Eric S., Lacey, Brian M., Tomaras, Andrew P., Evdokimov, Artem, Miller, J. Richard, Shanmugasundaram, Veerabahu
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009787/
https://ncbi.nlm.nih.gov/pubmed/21135211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013092107
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