Preparation, Gram-Negative Antibacterial Activity, and Hydrolytic Stability of Novel Siderophore-Conjugated Monocarbam Diols

[Image: see text] A novel series of monocarbam compounds exhibiting promising antibacterial activity against multidrug resistant Gram-negative microorganisms is reported, along with the synthesis of one such molecule MC-1 (1). Also reported are structure−activity relationships associated with the in...

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Autores principales: Flanagan, Mark E., Brickner, Steven J., Lall, Manjinder, Casavant, Jeffrey, Deschenes, Laura, Finegan, Steven M., George, David M., Granskog, Karl, Hardink, Joel R., Huband, Michael D., Hoang, Thuy, Lamb, Lucinda, Marra, Andrea, Mitton-Fry, Mark, Mueller, John P., Mullins, Lisa M., Noe, Mark C., O'Donnell, John P., Pattavina, David, Penzien, Joseph B., Schuff, Brandon P., Sun, Jianmin, Whipple, David A., Young, Jennifer, Gootz, Thomas D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2011
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018130/
https://ncbi.nlm.nih.gov/pubmed/24900319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200012f
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