Preparation, Gram-Negative Antibacterial Activity, and Hydrolytic Stability of Novel Siderophore-Conjugated Monocarbam Diols

[Image: see text] A novel series of monocarbam compounds exhibiting promising antibacterial activity against multidrug resistant Gram-negative microorganisms is reported, along with the synthesis of one such molecule MC-1 (1). Also reported are structure−activity relationships associated with the in...

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Main Authors: Flanagan, Mark E., Brickner, Steven J., Lall, Manjinder, Casavant, Jeffrey, Deschenes, Laura, Finegan, Steven M., George, David M., Granskog, Karl, Hardink, Joel R., Huband, Michael D., Hoang, Thuy, Lamb, Lucinda, Marra, Andrea, Mitton-Fry, Mark, Mueller, John P., Mullins, Lisa M., Noe, Mark C., O'Donnell, John P., Pattavina, David, Penzien, Joseph B., Schuff, Brandon P., Sun, Jianmin, Whipple, David A., Young, Jennifer, Gootz, Thomas D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2011
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018130/
https://ncbi.nlm.nih.gov/pubmed/24900319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200012f
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