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A Novel (18)F-Labeled Imidazo[2,1-b]benzothiazole (IBT) for High-Contrast PET Imaging of β-Amyloid Plaques
[Image: see text] (18)F-labeled imidazo[2,1-b]benzothiazole ([(18)F]8) was synthesized and evaluated as a tracer for cerebral β-amyloid deposits (Aβ) by means of positron emission tomography (PET). [(18)F]8 exhibits a high affinity to Aβ and suitable brain uptake kinetics combined with a high metabo...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4018122/ https://ncbi.nlm.nih.gov/pubmed/24900362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200123w |
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