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Bisdionin C—A Rationally Designed, Submicromolar Inhibitor of Family 18 Chitinases
[Image: see text] Chitinases of the GH18 family play important roles in a variety of pathogenic organisms and have also been shown to be involved in human asthma progression, making these enzymes potential drug targets. While a number of potent GH18 chitinase inhibitors have been described, in gener...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Chemical Society
2011
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4018065/ https://ncbi.nlm.nih.gov/pubmed/24900325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200008b |
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