Llwytho...

Natural product-guided discovery of a fungal chitinase inhibitor

Natural products are often large, synthetically intractable molecules, yet frequently offer surprising inroads into previously unexplored chemical space for enzyme inhibitors. Argifin is a cyclic pentapeptide that was originally isolated as a fungal natural product. It competitively inhibits family...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rush, Christina L., Schüttelkopf, Alexander W., Hurtado-Guerrero, Ramon, Blair, David E., Ibrahim, Adel F.M., Desvergnes, Stéphanie, Eggleston, Ian M., van Aalten, Daan M.F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518266/
https://ncbi.nlm.nih.gov/pubmed/21168763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2010.07.018
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