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Acetazolamide-based fungal chitinase inhibitors

Chitin is an essential structural component of the fungal cell wall. Chitinases are thought to be important for fungal cell wall remodelling, and inhibition of these enzymes has been proposed as a potential strategy for development of novel anti-fungals. The fungal pathogen Aspergillus fumigatus pos...

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Detalhes bibliográficos
Main Authors: Schüttelkopf, Alexander W., Gros, Ludovic, Blair, David E., Frearson, Julie A., van Aalten, Daan M.F., Gilbert, Ian H.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997425/
https://ncbi.nlm.nih.gov/pubmed/21044846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.09.062
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