Screening-based discovery of drug-like O-GlcNAcase inhibitor scaffolds

Lignende værker

• GlcNAcstatins are nanomolar inhibitors of human O-GlcNAcase inducing cellular hyper-O-GlcNAcylation
  af: Dorfmueller, Helge C., et al.
  Udgivet: (2009)
• Cell-Penetrant, Nanomolar O-GlcNAcase Inhibitors Selective against Lysosomal Hexosaminidases
  af: Dorfmueller, Helge C., et al.
  Udgivet: (2010)
• An efficient and versatile synthesis of GlcNAcstatins—potent and selective O-GlcNAcase inhibitors built on the tetrahydroimidazo[1,2-a]pyridine scaffold
  af: Borodkin, Vladimir S., et al.
  Udgivet: (2010)
• GlcNAcstatin - a picomolar, selective O-GlcNAcase inhibitor that modulates intracellular O-GlcNAcylation levels
  af: Dorfmueller, Helge C., et al.
  Udgivet: (2006)
• O-GlcNAcase fragment discovery with fluorescence polarimetry
  af: Borodkin, Vladimir S., et al.
  Udgivet: (2018)