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Functional Overlaps Between XLF and The ATM-dependent DNA Double Strand Break Response

Developing B and T lymphocytes generate programmed DNA Double Strand Breaks (DSBs) during the V(D)J recombination process that assembles exons that encode the antigen-binding variable regions of antibodies. In addition, mature B lymphocytes generate programmed DSBs during the Immunoglobulin Heavy ch...

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Bibliographic Details
Main Authors: Kumar, Vipul, Alt, Frederick W., Oksenych, Valentyn
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017585/
https://ncbi.nlm.nih.gov/pubmed/24674624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.01.010
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