ATM-dependent ERK signaling via AKT in response to DNA double-strand breaks

Ionizing radiation (IR) triggers many signaling pathways primarily originating from either damaged DNA or non-nuclear sources such as growth factor receptors. Thus, to study the DNA damage-induced signaling component alone by irradiation would be a challenge. To generate DNA double-strand breaks (DS...

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Bibliographic Details
Main Authors: Khalil, Ashraf, Morgan, Rhiannon N, Adams, Bret R, Golding, Sarah E, Dever, Seth M, Rosenberg, Elizabeth, Povirk, Lawrence F, Valerie, Kristoffer
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230515/
https://ncbi.nlm.nih.gov/pubmed/21263216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.3.14713
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